A hangover.
Always "tener guayabo" or "estar enguayabado." Colombians also use "guayabo moral" for the emotional hangover — the regret that arrives with the headache.
From the guava tree. One story says workers slept it off under guayabos; another links it to the sour, wrung-out feeling of the fruit.
Mexico says cruda, Spain says resaca, Chile says caña.
Reading a definition isn't the same as saying it to someone. Lingo Kaiava is a voice tutor set to Colombian Spanish — it uses guayabo the way locals do, corrects you in the moment, and never "fixes" the way real people actually talk into textbook Colombian Spanish.
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